Publikationen Hochschule für Life Sciences

• Advancing in-vitro drug precipitation testing: new process monitoring tools and a kinetic nucleation and growth model

• Amidophenol-Modified Amphiphilic Calixarenes: Synthesis, Interfacial Self-Assembly, and Acetaminophen Crystal Nucleation Properties

• Changes in Global Gene Expression by the UV Filter Benzophenone-3 in Zebrafisch (Danio Rerio)

• Combined Speciation Analysis by X-ray Absorption Near-Edge Structure Spectroscopy, Ion Chromatography, and Solid-Phase Microextraction Gas Chromatography-Mass Spectrometry To Evaluate Biotreatment of Concentrated Selenium Wastewaters

• Conformational polymorphism and amphiphilic properties of resorcinarene octapodands

• Cyclodextrin-based polyurethanes act as selective molecular recognition materials of active pharmaceutical ingredients (APIs)

• Effects of the Protein Kinase Inhibitor PKC412 on Gene Expression and Link to Physiological Effects in Zebrafish Danio rerio Eleuthero-Embryos

• Effects of the UV-filter 2-ethyl-hexyl-4-trimethoxycinnamate (EHMC) on expression of genes involved in hormonal pathways in fathead minnows (Pimephales promelas) and link to vitellogenin induction and histology

• NAPTIS - Nanotechnology Improved Titanium Implant Surfaces

• Oral self-emulsifying drug delivery systems, from biopharmaceutical to technical formulation aspects.

• Purification and characterization of hydroquinone dioxygenase from Sphingomonas sp. strain TTNP3

• Selenium speciation in acidic environmental samples: Application to acid rain-soil interaction at Mount Etna volcano

• Shedding Light on Selenium Biomineralization: Proteins Associated with Bionanominerals

• The UV-absorber benzophenone-4 alters transcripts of genes involved in hormonal pathways in zebrafish (Danio rerio) eleuthero-embryos and adult males

• Using Membrane-Supported LiquidLiquid Extraction for the Measurement of Extraction Kinetics

• A kinetic analysis of leaf uptake of COS and its relation to transpiration, photosynthesis and carbon isotope fractionation

• A simple approach to improve the sensitivity of enzyme-linked immunosorbent assay: Using the IMAPlate 5RC96 for result readout

• A tentative environmental risk assessment of the UV-filters 3-(4-methylbenzylidene-camphor), 2-ethyl-hexyl-4-trimethoxycinnamate, benzophenone-3, benzophenone-4 and 3-benzylidene camphor

• Activation of the JAK–STAT intracellular pathway in human retinal pigment epithelial cell line ARPE-19

• Advancing Pharmaceutical Dry Milling by Process Analytics and Robustness Testing

• Assessment of uptake and toxicity of fluorescent silica nanoparticles in zebrafish (Danio rerio) early life stages

• Augmented Feedback System to Support Physical Therapy of Non-specific Low Back Pain

• Biofunctionalization of dispense-plotted hydroxyapatite scaffolds with peptides: Quantification and cellular response

• Cell transfection using layer-by-layer (LbL) coated calixarene-based solid lipid nanoparticles (SLNs)

• Chromexposition und Galvanikbetriebe

• Comparison of different in vitro tests to assess oral lipid-based formulations using a poorly soluble acidic drug

• Cytokine signaling in the human brain capillary endothelial cell line hCMEC/D3

• Determination of strain fields in porous shape memory alloys using micro-computed tomography

• Different modes of dynamic image analysis in monitoring of pharmaceutical dry milling process

• Ecotoxicology of engineered nanoparticles

• Effects of diazepam on gene expression and link to physiological effects in different life stages in zebrafish Danio rerio

• Flowability characterisation of drug-excipient blends using a novel powder avalanching method

• Highly active human pharmaceuticals in aquatic systems: A concept for their identification based on their mode of action

• Identification of a CYP3A form (CYP3A126) in fathead minnow (<i>Pimephales promelas</i>) and characterisation of putative CYP3A enzyme activity

• In Situ Treatment of Thermal RF Plasma Processed Nanopowders to Control their Agglomeration and Dispersability

• Inducible and constitutive promoters for genetic systems in Sulfolobus acidocaldarius

• Investigating the porosity of 3D printed calcium phosphate scaffolds

• LANCE: Laccase-nanoparticle conjugates for the elimination of micropollutants (endocrine disrupting chemicals) from wastewater in bioreactors

• Laccase-modified silica nanoparticles efficiently catalyze the transformation of phenolic compounds

• Macrocyclic Molecules for the Design of Self-Assembling Amphiphiles

• Managed aquifer recharge with reclaimed water: approaches to a European guidance framework

• Mechanical implications of pneumatic neck vertebrae in sauropod dinosaurs

• Mit Cleaner Production zu mehr Ressourceneffizienz

• Novel Grafting Procedure of Ruthenium 2,2':6',2-Terpyridine Complexes with Phosphonate Ligands to Titania for Water Splitting Applications

• Options for water scarcity and drought management - the role of desalination

• Para-Carboxy Modified Amphiphilic Calixarene, Self-Assembly and Interactions with Pharmaceutically-Relevant Molecules

• Permeate flux decline in cross-flow microfiltration at constant pressure

• Properties of NiTi-structures fabricated by selective laser melting

• Properties of polyethersulfone ultrafiltration membranes modified by polyelectrolytes

• Quantification of pathogenic microorganisms and microbial indicators in three wastewater reclamation and managed aquifer recharge facilities in Europe

• Rapid incorporation and short-term distribution of a nonylphenol isomer and the herbicide MCPA in soil-derived organo-clay complexes

• Reverse protein arrays as novel approach for protein quantification in muscular dystrophies

• Selectivity of polyamide nanofiltration membranes for cations and phosphoric acid

• Self-assembly of amphiphilic calixarenes and resorcinarenes in water

• Some flame retardants and the antimicrobials triclosan and triclocarban enhance the androgenic activity in vitro

• Stereotactic implantation of deep brain stimulation electrodes: a review of technical systems, methods and emerging tools

• Study of a Standardized Taurocholate–Lecithin Powder for Preparing theBiorelevant Media FeSSIF and FaSSIF

• The Structure of Ca2+ Sensor Case16 Reveals the Mechanism of Reaction to Low Ca2+ Concentrations

• The apparent solubilizing capacity of simulated intestinal fluids for poorly water-soluble drugs

• The archaeo-eukaryotic primase of plasmid pRN1 requires a helix bundle domain for faithful primer synthesis

• The ecological impact of membrane-based extraction of phenolic compounds - a life cycle assessment study

• Validity of a power law approach to model tablet strength as a function of compaction pressure

• Valuing the subsurface pathogen treatment barrier in water recycling via aquifers for drinking supplies

• Widespread occurrence of estrogenic UV-filters in aquatic ecosystems in Switzerland

• 5-hydroxyindole-2-carboxylic-acid-amides-novel-histamine-3-receptor-treatment-obesity

• A Microtiter-Plate Based Cytochrome P4503A Activity Assay in Fish Cell Lines

• A process analytical technology (PAT) for the milling and handling of pharmaceutical powders and granules

• A systematic dilution study of self-microemulsifying drug delivery systems in artificial intestinal fluid using dynamic laser light backscattering

• An Investigation of Computer-Generated Visual Feedback for the Support of Low Back Pain Therapy

• Analysis and Surface Modification of Rapid Prototyped Titanium Structures.

• Applications of Nanoparticles to Water Splitting

• Backtrainer - Ein System zur Unterstützung der Therapie von chronischen Rückenschmerzpatienten

• Backtrainer- Computer-aided Therapy System with Augmented Feedback for the Lower Back

• Backtrainer: Computer-aided therapy with augmented feedback for the lower back

• Balsa Raft Crossing the Pacific Finds Low Contaminant Levels

• Bioaugmentation of UASB reactors with immobilized Sulfurospirillum barnesii for simultaneous selenate and nitrate removal

• Biological Production of Selenium Nanoparticles from Waste Waters

• Biological Selenium Remediation - A Simple Process Complicated.

• Capillary nanofiltration coupled with powdered activated carbon adsorption for high quality water reuse

• Contact position analysis of deep brain stimulation electrodes on post-operative CT images

• Continuous-phase drug concentration as driving force for (trans)dermal drug delivery with lipophilic vehicles

• Craniomaxillofacial fibrous dysplasia: a 10-year database 1996-2006

• Critical concentrations in the dilution of oral self-microemulsifying drug delivery systems

• Degradation of phenolic endocrine disruptors to improve biological wastewater treatment

• Der sterile Arztkittel - Traum oder Wirklichkeit

• Design of a high-throughput device for screening surface modification protocols

• Development of a cytochrome P450 3A assay for toxicological assessment of pharmaceuticals in fish cells

• Development of an intraoperative visualisation tool for electrode placement in deep brain stimulation

• Disposable cantilever sensors for biomedicine

• Eco-efficient technologies for a sustainable agriculture

• Effects of lipid-lowering pharmaceuticals bezafibrate and clofibric Acid on lipid metabolism in fathead minnow (pimephales promelas)

• Establishment of a High Resolution Melting assay for genetic differentiation of soft wheat from spelt

• Estrogenic activity of ternary UV filter mixtures in fish (Pimephales promelas) -- An analysis with nonlinear isobolograms

• Expanding and understanding the genetic toolbox of the hyperthermophilic genus Sulfolobus

• Extraction of tannins from organic waste as a pre-treatment to biogas production

• Fabrication of TiO2-coated epoxy replicas with identical dual-type surface topographies used in cell culture assays

• Facial acquisition by dynamic optical tracked laser imaging: a new approach

• Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides as potent, orally available mGlu1 receptor enhancers

• Generation of a genetically-engineered cell line for Identification of PepT1 Substrates

• Generation of three-dimensional prototype models based on cone beam computed tomography

• Gras effizient trocknen

• Identification of a CYP3A form (CYP3A126) in fathead minnow (Pimephales promelas) and characterisation of putative CYP3A enzyme activity

• Impact of bio-augmentation with Sphingomonas sp. strain TTNP3 in membrane bioreactors degrading nonylphenol

• Impact of bio-augmentation with Sphingomonas sp. strain TTNP3 in membrane bioreactors degrading nonylphenol

• Impact of wetting agents on the filtration performance of polymeric ultrafiltration membranes

• Improved osseointegration of a novel, hydrophilic Ti surface - a review

• Influence of Structurally Diverse Lipid Containing Drug Formulations on the Transport of Lipophilic Drugs through;Caco-2 Cell Monolayer

• Influence of molecular properties on oral bioavailability of lipophilic drugs - mapping of bulkiness and different measures of polarity

• Integrated Silicon Nanowire Sensor Platform for molecular diagnostics

• Interactive Visualization - A Survey

• Key Performance Indicators for Chemical Plants

• Key performance indicators for chemical plants

• Kits and Tools for in-vitro Diagnostics

• Laccase-Nanoparticle Conjugates for the Elimination of micropollutants from wastewater in bioreactors

• M.P.4.07 Reverse protein arrays for efficient protein diagnosis of muscular dystrophies in less than 10 mg muscle tissue

• Membrane bioreactor technology for removal of organic micropollutants

• Modification and analysis of titanium structures for implants

• Molecular biology of the pRN1 plasmid from Sulfolobus islandicus

• Nanoparticles Fate in AQuatic environment: Development of an environmental risk assessment tool

• New electrophysiological mapping combined with MRI in parkinsonian’s subthalamic region

• Observation of cake layer formation and removal on microporous hollow-fibre membranes

• Polyelectrolyte-modified polyethersulfone ultrafiltration membranes for wastewater treatment applications

• Produktion von Biogas aus vorbehandelten Bananenabfällen in Costa Rica

• Quantification of the influence of extracellular laccase and intracellular reactions on the isomer-specific biotransformation of the xenoestrogen technical nonylphenol by the aquatic hyphomycete Clavariopsis aquatica

• RECLAIM WATER - manage aquifer recharge for safe indirect potable reuse

• Radio (14C)- and fluorescent-doubly labeled silica nanoparticles for biological and environmental toxicity assessment

• Rapid Implant Manufacturing

• Rapid Manufacturing of Individualized Ti-6Al-4V Bone Implants.

• Regulation of BCRP (ABCG2) and P-Glycoprotein (ABCB1) by Cytokines in a Model of the Human Blood–Brain Barrier

• Repositioning precision of EEG-Caps û a preliminary study

• Ressourceneffizienz in der Bauwirtschaft

• Silicone moulding for pressure sore debridement

• Sorption behavior of potential organic wastewater indicators with soils

• Sulfur K-edge XANES spectroscopy as a tool for understanding sulfur chemical state in anaerobic granular sludge

• The GTZ-Holcim strategic alliance on co-processing waste material in cement production - A success story we can build on.

• The effect of cadmium on brain cells in culture

• The essential toxin: the changing perception of selenium in environmental sciences

• The human brain endothelial cell line hCMEC/D3 as a blood-brain barrier model for drug transport

• Treatment of landfill leachate in a bench scale MBR

• Vorteile bei Verwendung von Wachsbitumen im Strassenbau

• Water recycling in Europe and the Mediterranean: framework conditions and technologies for future development

• Zinc and copper removal from sand blasting materials and solid residues of thermal processes

• Amino-Substituted Amphiphilic Calixarenes: Self-Assembly and Interactions with DNA

• Assessment of the stability of TGFbeta 3 bioactivity for potential bioreactor applications

• Automated in situ analysis of volatile sulfur gases using a Sulfur Gas Analyser (SUGAR) based on cryogenic trapping and gas-chromatographic separation

• Biodegradation: The Reason for the Inefficiency of Small Organic Acids in Chelant-Assisted Phytoextraction

• Biological Alkylation and Colloid Formation of Selenium in Methanogenic UASB Reactors

• Characterization of (R,S)-5,7-di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one (rac-BHFF) as a positive allosteric modulator of GABA-B receptor

• Cleaner Production und Transfer von umweltfreundlichen Technologien

• Computational aqueous solubility prediction for drug-like compounds in congeneric series

• Controlling silica nanoparticle properties for biomedical applications through surface modification

• Development and characterization of P-glycoprotein 1 (Pgp1, ABCB1)-mediated doxorubicin-resistant PLHC-1 hepatoma fish cell line

• Dimethyl fumarate, a small molecule drug for psoriasis, inhibits Nuclear Factor-kB and reduces myocardial infarct size in rats

• Does abdominoplasty with liposuction of the love handles yield a shorter scar? An analysis with abdominal 3D laser scanning

• Drug absorption modeling as a tool to define the strategy in clinical formulation development

• Drug targeting using OX7-immunoliposomes: Correlation between Thy 1.1 antigen expression and tissue distribution in the rat

• Drug-excipient interactions by Vitamin E-TPGS: In vitro studies on inhibition of P-glycoprotein and colonic drug absorption

• Effect of sludge treatment on the bioaccumulation of nonylphenol in grass grown on sludge-amended soil

• Effects of Pharmaceuticals on Aquatic Organisms

• Endocrine active UV filters: developmental toxicity and exposure through breast milk

• Establishment of a miniaturized enzyme-linked immunosorbent assay for human transferrin quantification using an intelligent multifunctional analytical plate

• Factors affecting the removal of organic micropollutants from wastewater in conventional treatment plants (CTP) and membrane bioreactors (MBR)

• Fate in soil of 14C-sulfadiazine residues contained in the manure of young pigs treated with a veterinary antibiotic

• Fate of a branched nonylphenol isomer in submerged paddy soils amended with nitrate

• Genetic tools for Sulfolobus spp.: vectors and first applications

• Human pharmaceuticals modulate P-gp1 (ABCB1) transport activity in the fish cell line PLHC-1

• Impact of sewage sludge conditioning and dewatering on the fate of nonylphenol in sludge-amended soils

• In silico prediction of brain and CSF permeation of small molecules using PLS regression models

• Molecular modeling and functional characterization of the monomeric primase-polymerase domain from the Sulfolobus solfataricus plasmid pIT3

• Mutation and reversion frequencies of different Sulfolobus species and strains

• Nanoparticulate systems: a new competence platform at the University of Applied Sciences Northwestern Switzerland (FHNW)

• Selenate removal in methanogenic and sulfate-reducing upflow anaerobic sludge bed reactors

• Selenium Speciation Assessed by X-Ray Absorption Spectroscopy of Sequentially Extracted Anaerobic Biofilms

• Selenium oxyanion inhibition of hydrogenotrophic and acetoclastic methanogenesis

• Simultaneous trace determination of nine organic UV-absorbing compounds (UV filters) in environmental samples

• Synthesis and characterization of 1,3-dihydro-benzo[b][1,4]diazepin-2-one derivatives: Part 3. New potent non-competitive metabotropic glutamate receptor 2/3 antagonists

• The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies

• The role of sludge conditioning and dewatering in the fate of nonylphenol in sludge-amended soils

• UV Filters in the Aquatic Environment Induce Hormonal Effects and Affect Fertility and Reproduction in Fish

• Use of FLIPR membrane potential dyes for validation of high-throughput screening with the FLIPR and micro ARCS technologies: identification of ion channel modulators acting on the GABAA receptor

• para-Acylcalix[n]arenes: from molecular to macroscopic assemblies

• A potentiometric titration method for the crystallization of drug-like organic molecules

• Absorption of poorly water soluble drugs subject to apical efflux using phospholipids as solubilizers in the Caco-2 cell model

• Application of a Statistical Method to the Absorption of a New Model Drug from Micellar and Lipid Formulations - Evaluation of Qualitative Excipient Effects

• Behavior of two differently radiolabeled 17alpha -ethinylestradiols continuously applied to a laboratory-scale membrane bioreactor with adapted industrial activated sludge

• Bestimmung von Enniatinen in Getreideprodukten aus dem Schweizer Markt.

• Computer-assisted single- or double-cut oblique osteotomies for the correction of lower limb deformities

• Contamination by Selected Organochlorine Pesticides (OCPs) in Surface Soils in Hanoi, Vietnam

• Contribution to the detection and identification of oxidation metabolites of nonylphenol in Sphingomonas sp. strain TTNP3

• Degradation pathway of bisphenol A: does ipso substitution apply to phenols containing a quaternary alpha -carbon structure in the para position?

• Effects of the UV filter benzophenone-2 on reproduction in fish

• Evaluation of an optimization module for single- and double-cut oblique osteotomy based correction of deformed long bone

• Fluoroscopic navigation system for hip surface replacement

• Individualisierte Implantate aus dem 3-D Drucker

• Laser scanner analysis in reconstruction of traumatic laceration of the facial nerve

• Level and Distribution of Polychlorinated Biphenyls (PCBs) in Surface Soils from Hanoi, Vietnam

• Massgeschneiderte J2ME-Anwendungen

• Mitverwertung von Abfällen in der Zementproduktion - Erfahrungen aus Entwicklungsländern;Co-processing waste material in cement production - Experience from developing countries

• Neuartige In-vitro-Diagnostik auf Basis moderner Technologien

• Permanent Fish Cell Cultures as Important Tools in Ecotoxicology

• Prozessanalytische Technologie (PAT) für die Mahlung und Förderung pharmazeutischer Pulver

• Rational design, synthesis, and structure-activity relationship of benzoxazolones: New potent mglu5 receptor antagonists based on the fenobam structure

• Reduktion von Treibhausgasen in Jordanien

• Role of dissolved humic acids in the biodegradation of a single isomer of nonylphenol by Sphingomonas sp

• Silber/Silica-Nanopartikel als Additive für Polymere mit antimikrobieller Wirkung

• Surface modification of resorcinarene based self-assembled solid lipid nanoparticles for drug targeting

• Synthesis and biological evaluation of fenobam analogs as mGlu5 receptor antagonists

• T-Scan: First Experiences with Acquisition of Cleft Morphology

• Time resolved analysis of molecular interactions using nanomechanical cantilever sensors

• Umweltverträgliche Abfallentsorgung

• Umweltverträgliche Entsorgung von Abfällen

• Wie wirken UV-absorbierende Chemikalien auf das Hormonsystem?

• kotoxikologie

• A strategy for preclinical formulation development using GastroPlus as pharmacokinetic simulation tool and a statistical screening design applied to a dog study

• A technical feasibility study of surfactant-free drug suspensions using octenyl succinate-modified starches

• An extended model based on the modified Nernst-Planck equation for describing transdermal iontophoresis of weak electrolytes

• Bausperrgut - Baustoff von morgen

• Biomechanical evaluation of the interfacial strength of a chemically modified sandblasted and acid-etched titanium surface

• Biomimetic modification of titanium dental implant model surfaces using the RGDSP-peptide sequence: A cell morphology study

• Chemistry is a fundamental element for novel education in molecular life sciences

• Comparison of In Vitro and In Vivo Estrogenic Activity of UV Filters in Fish

• Cutaneous metabolism of a dipeptide influences the iontophoretic flux of a concomitant uncharged permeant

• Cyclodextrin derivatives as chiral supramolecular receptors for enantioselective sensing

• Cytotoxicity of pharmaceuticals found in aquatic systems: Comparison of PLHC-1 and RTG-2 fish cell lines

• Enhancing surface free energy and hydrophilicity through chemical modification of microstructured titanium implant surfaces

• Estrogenic activity of UV filter mixtures

• Estrogenic activity of pharmaceuticals and pharmaceutical mixtures in a yeast reporter gene system

• Fate of a 14C-Labeled Nonylphenol Isomer in a Laboratory-Scale Membrane Bioreactor

• G3139 and Other CpG-Containing Immunostimulatory Phosphorothioate Oligodeoxynucleotides Are Potent Suppressors of the Growth of Human Tumor Xenografts in Nude Mice

• Identification of isomeric 4-nonylphenol structures by gas chromatography-tandem mass spectrometry combined with cluster analysis

• Laser surface scanning analysis in reconstructive rhytidectomy

• Microbial degradation of nonylphenol and other alkylphenols-our evolving view

• Molekulare Regulation der Bildung und Inaktivierung reaktiver Sauerstoffspezies

• Multiple hormonal activities of UV filters and comparison of in vivo and in vitro estrogenic activity of ethyl-4-aminobenzoate in fish

• Persuasiveness of a Mobile Lifestyle Coaching Application Using Social Facilitation

• Quantitative assessment of tissue retention, lipophilicity, ionic valence and convective transport of permeant as factors affecting iontophoretic enhancement

• Quantitative concepts in drug formulation and absorption and their relevance for drug delivery

• Surface modification of polyacrylonitrile with nitrile hydratase and amidase from Agrobacterium tumefaciens

• Sustained polymer membranes fabricated by nanoimprint lithography

• T-Scan: Ein handgeführter Laserscanner für die medizinische Applikation in der Kiefer-Gesichtschirurgie

• The Ultraviolet Filter 3-Benzylidene Camphor Adversely Affects Reproduction in Fathead Minnow (Pimephales promelas)

• The degradation of a-quaternary nonylphenol isomers by Sphingomonas sp. strain TTNP3 involves a type II ipso -substitution mechanism

• Time domain 1H NMR as a new method to monitor softening of gelatin and HPMC capsule shells

• Topical bioavailability of triamcinolone acetonide: effect of dose and application frequency

• Virtuelle Operationsplanung

• Worldwide Occurrence of Organotins from Antifouling Paints and Effects in the Aquatic Environment

• kotoxikologische Wirkungen von Pharmazeutikarückständen auf aquatische Organismen