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Forschungsseminar Vorlesung von Paula Guerrero

Synthetic Glycolipids Rescue Biosynthesis Deficiencies of GPI-Anchored Protein, Paula Guerrero PhD Student, Institute for Chemistry and Bioanalytics, Hochschule für Life Sciences FHNW

The objective of this project was to employ synthetic GPI fragments to rescue the production of GPI-Anchored Proteins (GPI-APs) and treat Inherited GPI Disorders caused by mutations affecting the initial steps of the GPI biosynthesis. We designed and synthesized 5 glycolipids that resemble the products/substrates of the enzymes involved in those steps and, to our delight, they were efficiently incorporated into the treated cells and restored the GPI-APs expression.

Datum und Zeit

18.05.2022 12:30 - 13:15 iCal

Ort

Hörsaal 02.S.21

FHNW Campus Muttenz, Hofackerstrasse 30, 4132 Muttenz

Veranstaltet durch

Hochschule für Life Sciences

Kosten

Eintritt frei

FHNW Campus Muttenz

Fachhochschule Nordwestschweiz FHNW Hofackerstrasse 30 4132 Muttenz
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