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Forschungsseminar Vortrag von Prof. Benjamin Engel

Exploring the molecular architecture of photosynthesis and carbon fixation with cryo-electron tomography, Prof. Benjamin Engel, Biozentrum, University of Basel

Cells accomplish the biochemical reactions of life by concentrating their proteins into a variety of subcellular compartments called organelles. Our group explores the relationship between the form of the organelle and the function of its resident macromolecules. How does organelle architecture direct molecular function, and reciprocally, how do macromolecules sculpt and shape organelles? To investigate these questions, we use focused ion beam (FIB) milling of frozen cells followed by cryo-electron tomography to image macromolecules within their native cellular environment. Through a combination of nanometer-precision localization and high-resolution structural analysis, we aim to chart the molecular landscapes of organelles.

In this talk, we will explore the molecular architecture of light-harvesting thylakoid membranes in cyanobacteria, green algae, and plants (Rast et al., 2019; Wietrzynski et al., 2020). I will also describe our recent work on VIPP1, a conserved membrane-remodeling protein that is required for thylakoid biogenesis and maintenance (Gupta et al., 2021). We will then journey through to the pyrenoid, a carbon-fixing subcompartment of the chloroplast that is formed by liquid-liquid phase separation (Freeman Rosenzweig et al., 2017; He et al., 2020). Finally, will look at a highly efficient method of CO2 capture in anerobic bacteria, where HDCR electrical nanowires couple hydrogen splitting to carbon fixation (Dietrich et al. 2022).

Datum und Zeit

30.11.2022 12:30 - 13:15 iCal


Hörsaal 02.S.21

FHNW Campus Muttenz, Hofackerstrasse 30, 4132 Muttenz

Veranstaltet durch

Hochschule für Life Sciences


Eintritt frei

Der Referent ist eine Gast von

Prof. Dr. Sebastian Wendeborn
Prof. Dr. Sebastian Wendeborn Leiter Institut für Chemie und Bioanalytik
Telefon : +41 61 228 55 45 (Direkt)

FHNW Campus Muttenz

Fachhochschule Nordwestschweiz FHNW Hofackerstrasse 30 4132 Muttenz
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