South Africa’s socio-economic development is dramatically affected by the spread of HIV/Aids with high rates of child and maternal mortality. While effective health care would be needed to improve the situation, health workers and in particular nurses and midwifes in rural areas lack access to health information and education. The increasing number of mobile phones and the rising popularity of social networking sites and tools can be harnessed to improve access to evidence-based information and education. In developing and researching new educational approaches, South Africa can act as a role model and facilitator for Africa and beyond.