Computer-assisted modelling of wastewater treatment is becoming more and more popular and is particularly useful for the design and optimization of wastewater treatment plants. Popular models such as the Activated Sludge Model No. 3 (ASM3) consist of a series of differential equations which describe biochemical reactions which occur during biological…

Host cell proteins (HCPs) are one of the major process-related impurities of therapeutic protein production based on biological systems such as Chinese hamster ovary (CHO) cells. For clinical application of biopharmaceuticals, the control of HCP is crucial for product stability, product quality and patient safety. This project aims to focus…

Notebooks, excel sheets, calendars, all on papers; how do we handle our daily information and data exchange? Sincerely, digitalization often lacks behind. The talk shall show on the example of the emerging HLS ‘open access platform’ for analytical equipment and spectra analysis tools why digitalization is a process that needs…

The combination of membrane-supported liquid-liquid extraction with inline concentration measurement of the two phases allows the mass transfer to be monitored continuously without additional offline analysis. Since mixing and separation of the two liquid phases is not required, the process can be operated continuously without long settling times. In discontinuous…