Cell biology and in vitro toxicology

Team leader Cell biology and in vitro toxicology: Prof. Dr. Laura Suter-Dick

Projects & News

Projects, Cell biology

Novel in vitro biomarkers for hepatotoxicity: exosomal miR-122

In vitro models for liver disease suffer from the lack of well-established and sensitive biomarkers of cellular damage. MicroRNAs (miRNAs; small noncoding RNAs) represent potential biomarkers for the detection of drug-induced liver injury in vivo and in vitro. Altered physiological state caused by disease or tissue damage results in altered release of exosomal- or protein-bound miRNAs, detectable in body fluids and cell culture media…

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