Projects

The institute covers a broad range of scientific areas that are applied to an equally broad variety of industrially relevant topics

Polymer Chemistry & Biomaterials, Projects

Oxidation of 5-HMF to 2,5-FDCA

The collective strive towards a more sustainable and circular economy converges academic and industrial efforts on the increased implementation of biobased raw materials to produce items of daily use such as packaging, bags, bottles etc. Among others, the conversion of carbohydrates to 5-HMF an finally to 2,5-FDCA is a promising…

Polymer Chemistry & Biomaterials, Projects

FFORTESS – Fluorine Free Omniphobic Roughness Tailored Extended Slippery Surfaces

In this Innosuisse funded Project (105.146.1 IP-ENG) we aim to develop robust fluorine free textile coatings for oil and water repellence. Up to date perfluorinated compounds (PFAS) are used for oil, stain and water repellence in the textile and coating industry. Due to environmental and health concerns such compounds will…

Polymer Chemistry & Biomaterials, Projects

Swiss HIPOGRAPH

In this Innosuisse funded Project (45921.1 IP-ENG) we developed a highly porous graphene based composite membrane for waterproof breathable applications via Chemical Vapor deposition. This breathable membrane was chemically functionalized and developed for textiles and related high end membrane applications. During the project methods for the selective chemical modification of…

Projects, Instrumental Analytics

Microplastic detecion in water samples

The increasing microplastic pollution in air, water and soil requires the development of robust and sensitive analytical methods to better understand and address the problem. Plastics are cheap, stable and corrosion resistant, making this class of materials attractive for many applications. Plastics consist of long chains of polymer molecules made…

Projects, BioInterfaces

Novel biocompatible and biodegradable polymers for biomedical applications

We design novel bio-based polymers to develop biocompatible and biodegradable nanocarriers as alternatives to e.g. PEG.

Projects, BioInterfaces

Multi-compartment nanofactories for on-site and on demand drug synthesis and delivery

We develop compartmentalized vesicles with internal compartments that can be triggered independently and selectively to release their cargo. Libraries of novel stimuli-responsive block co-polymers are prepared for vesicle formation, and release is actuated by external stimulus such as light, magnetic field, etc.

Projects, BioInterfaces

Nanocarriers for mRNA therapeutics

Combining the stability of polymers with transfection efficiency of lipids, we developed polymer-lipid hybrid nanoparticles, which can be stored as lyophilized powder and display long-term storage stability also in suspension. Lyophilization does not impair transfection efficiency.

Projects, BioInterfaces

Nanomedicine and theranostics

Diverse nanoparticle formulations based on polymers, lipids, and combinations thereof, loaded with (bio)therapeutics such as antimicrobial peptides, small molecule drugs, and nucleic acids are developed to combat infectious diseases and cancer. We further develop inorganic nanoparticles (metal and semiconductor) and drug-conjugated luminescent probes with cleavable linkers for simultaneous therapy and…

Projects, BioInterfaces

Tailor-made nanoparticles

Using top-down and bottom-up synthesis, encapsulation, surface engineering, and bioconjugation approaches, we develop nanoparticles with precisely defined and controlled size, morphology, composition, and surface functionality, and tailor them for the desired biological targets and functions.

Projects, Molecular Nanotechnology

RESTRAIN

The groundbreaking work that led to the emergence of metal-organic frameworks (MOFs) represents a major milestone in the design of materials with controlled atomic or molecular architectures. MOFs are organic-inorganic crystalline materials; they have attracted particular attention owing to their tremendously high surface area and tunable pore size, properties that…

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