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      Life Sciences
      Institut für Chemie und Bioanalytik
      Molekulare Nanotechnologie

      Molekulare Nanotechnologie

      Bottom-up design of nanomaterials for molecular recognition and (bio)catalysis.

      Biological systems possess the ability to recognize, sort, catalyze, communicate and to store information using a set of basic rules that are known in and of themselves but that interplay in such a complex, intricate and synergistic manner as to result in tremendous efficiency. The research activities of the molecular nanotechnology group takes its roots and inspiration in this vision and develop synthetic strategies to design novel, functional nanomaterials endowed with molecular recognition or biocatalytic properties.

      Designer macrocycles - The group has specialized in the design and synthesis of macrocyclic molecular receptors based on calixarenes and cyclodextrins. We apply those designer macrocycles as molecular recognition elements for small organic molecules (e.g., active pharmaceutical ingredients, natural products) for a range of environmental and biotech applications. Amphiphilic calixarenes are also used to produce crystalline two-dimensional assemblies (e.g., metal-organic networks), which are applied as crystallization templates.

      Protein Supramolecular engineering - In contrast to enzyme engineering, the term “supramolecular-engineering” refers to a novel concept of enzyme supramolecular modification, without manipulation of the protein sequence by genetic engineering or covalent modification of the biomolecule. We have developed this approach to design synthetic nanomaterials possessing unprecedented affinity and selectivity for protein targets such as viruses and virus-like particles. We have also applied this supramolecular approach to develop a novel class of nanobiocatalysts with applications ranging from specialty chemical (asymmetric) synthesis and production of biologics, to proteomics and nanomedicine.  

      Molekulare Nanotechnologie

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      Zusammenarbeit in Forschung und Dienstleistungen

      Life Sciences
      TeamÜbersicht Chemie und Bioanalytik
      Patrick Shahgaldian

      Prof. Dr. Patrick Shahgaldian

      Arbeitsgruppenleiter Molekulare Nanotechnologie

      Telefonnummer

      +41 61 228 54 87

      E-Mail

      patrick.shahgaldian@fhnw.ch

      Adresse

      Hochschule für Life Sciences FHNW Institut für Chemie und Bioanalytik Hofackerstrasse 30 4132 Muttenz

      cjlife sciencesforschungnanotechnologieicbbioanalytikmwforschungsfeldchemie

      Institut für Chemie und Bioanalytik

      Fachhochschule Nordwestschweiz FHNW
      Hochschule für Life Sciences
      Institut für Chemie und Bioanalytik

      Hofackerstrasse 30

      4132 Muttenz

      Telefon+41 61 228 55 45

      E-Mailsebastian.wendeborn@fhnw.ch

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