Dr. Christelle Jablonski

    Tätigkeiten an der FHNW

    • Wissenschaftliche Mitarbeiterin (Nanotechnology and Organic Chemistry)
    • Dozentin Molecular Life Sciences

    Lehre

    Praktikum

    • PCIT Chemical Engineering Grundlagen Praktikum
    • OC-Vertiefung Praktikum
    • Semesterarbeit OC-Spezialisierung
    • Bachelorthesis und Masterthesis supervision

    Unterricht

    • Bioorganic Chemistry (enzymatic reactions, yeast catalysis)
    • 1D and 2D NMR spectroscopy: Molecular Life Sciences studies
    • Applied Organic Chemistry in Master of Science in Life Sciences

    Forschung

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    Profil

    • Article: Novel adenosine A2AR ligands: A synthetic, functional and computational investigation of selected literature adenosine A2AR antagonists for extending into extracellular space. Bioorganic and Medicinal Chemistry Letters, published in 2013
    • GÜLLER, J. SCHRÖER, C. LORIN, New method for carrying out a chemical reaction, WO 02/13969 A1
    • LORIN, C. MAROT, V. GARDON & P. ROLLIN : Novel approach to the synthesis of sugar sulfones via trans-sulfonylation of a unique heteroaryl precursor, Tetrahedron Lett., 1995, 36, 4437-4438.
    • M.T. LAKIN, N. MOUHOUS-RIOU, C. LORIN, P. ROLLIN, J. KROON & S. PEREZ : Structural analysis of 6-S-(benzoxazol-2-yl)-6-deoxy-1,2:3,4-di-O-isopropylidene-6-thio-a-D-galactopyranose by means of X-ray diffraction, high resolution NMR spectroscopy and molecular modelling, Carbohydr. Res., 1996, 290, 125-136.
    • CASSEL, P. CHAIMBAULT, M. LAFOSSE, C. LORIN & P. ROLLIN : Sugar-derived sulfoxides and their reactivity towards Pummerer rearrangement conditions, Sulfur Lett., 1996, 20, 63-70.
    • MAVRATZOTIS, V. DOURTOGLOU, C. LORIN & P. ROLLIN : Glucosinolate chemistry. First synthesis of glucosinolates bearing an external thio-function, Tetrahedron Lett., 1996, 37, 5699-5700.
    • MORAVCOVA, P. ROLLIN, C. LORIN, V. GARDON, J. CAPKOVA & J. MAZAC : Mechanism of regioselective thiofunctionalization of pentofuranoses, J. Carbohydr. Chem. , 1997, 16, 113-127.
    • H. BUIST, B. BEHROUZIAN, S. CASSEL, C. LORIN, P. ROLLIN, A. IMBERTY & S. PEREZ : Stereochemical analysis of D-galacto-sulfoxides using (S)-a-methoxyphenyl acetic acid, Tetrahedron : Asymm., 1997, 8, 1959-1961.
    •  J.-L. GRAS, X. FOURNIOUX, T. SOTO, C. LORIN & P. ROLLIN : Synthesis of carbohydrate formacetal dimers under non-acidic conditions, J. Carbohydr. Chem., 1997, 16, 1509-1514.
    • BROCHARD, C. LORIN, N. SPIESS & P. ROLLIN, A novel reductive fragmentation reaction in thio-sugar chemistry, Tetrahedron Lett., 1998, 39, 4267-4270.
    • IMBERTY, N. MOUHOUS-RIOU, P. ROLLIN, S. CASSEL, C. LORIN & S. PEREZ : Crystal and molecular structures of two aza-heterocyclic hybrids derived from 6-thio-D-galactopyranose, Carbohydr. Chem., 1998, 17, 923-936.
    • LORIN & P. ROLLIN, Synthesis of sugar-derived alkyl sulfones using a versatile transsulfonylation process, Synthesis, 1998, 1506-1510.
    • GUEYRARD, C. LORIN, J. MORAVCOVA & P. ROLLIN, A new intramolecular migration in thiosugar chemistry : S - O transfer of a benzothiazol-2-yl group in saccharidic sulfones, Carbohydr. Chem., 1999, 18, 3, 317-331.
    • JABLONSKI-LORIN, V. MELLILO, E. HUNGERBUEHLER, Stereoselective Bioreduction to a Chiral Building Block on a Kilogram Scale, Chimia, 2003, 57, 9, 574-576.
    • LORIN, V. AUCAGNE, A. TATIBOUET & P. ROLLIN, Regioselective Michael-induced cyclisation of g- and d-hydroxy vinyl sulfides and vinyl dithiocarbamates, Tetrahedron Letters, 2005, 46, 25, 4349-4352.
    • JABLONSKI-LORIN, M. NOLD, A. BODENMÜLLER, E. HUNGERBÜHLER,Versatile approaches to sugar amino acids building blocks, Chimia, 2007, 5, 286-288.
    • ALLES, R.; PUCHKOV, M.; JABLONSKI, C.; SPEICH, B.; KEISER, J.; HUWYLER, J., Development of oxantel tablets for pediatric clinical studies, Journal of Drug Delivery Science and Technology2013, 23(6), 623-625.
    • JABLONSKI, G. GRUNDLER, U. PIELES, S. STEBLER , R. OEHRLEIN AND Z. SZAMEL, Synthesis and electrophoretic properties of novel nanoparticles for colored electronic Ink and e-paper applications, Chimia, 2016, 70, 5, 366-368.

    Präsentationen und Poster

    • LORIN, C. MAROT & P. ROLLIN : Stereocontrolled synthesis of oxa- and azacycles from sugar-derived vinyl sulfones, 7th Meeting on Stereochemistry, 24-26 / 04 / 1995, Trest (République Tchèque)*.
    • MORAVCOVA, P. ROLLIN, C. LORIN, V. GARDON, J. MAZAC & J. CAPKOVA : Regioselective Mitsunobu thiofonctionalization of 1,2-isopropylidene-a-D-ribo- and xylofuranoses, ibid.
    • CASSEL, G. CATELANI, F. DE RENSIS, C. LORIN & P. ROLLIN : Valorisation non alimentaire du lactosérum. Synthèse régiosélective de dérivés du 6-thio-D-galactose : XVIèmes Journées Méditerranéennes des Glucides, 20-24 / 05 /1996, L’Isle sur la Sorgue.
    • CASSEL, C. LORIN & P. ROLLIN : Réarrangement de Pummerer de sulfoxydes osidiques, ibid.
    • LORIN & P. ROLLIN : Acétogénines d’Annonacées. Approches synthétiques d’oxacycles chiraux à partir de vinyl sulfures osidiques, ibid*.
    • LORIN & P. ROLLIN : Vinyl sulfures dérivés de sucres. Nouvelles approches régio- et stéréocontrolées pour la synthèse de systèmes oxacycliques chiraux, IXèmes Journées Franco-Espagnoles de Chimie Organique, 02-07 / 06 / 1996, Aspet*.
    • CASSEL, G. CATELANI, F. DE RENSIS, C. LORIN & P. ROLLIN : Sintesi regioselettiva di derivati del 6-tio-D-galattosio e del 6’-tiolattosio, TUMA 96, 06-07 / 06 / 1996, L’Aquila (Italie).
    • LORIN & P. ROLLIN : Sugar-derived vinyl sulfides. Novel regio- and stereocontrolled synthetic approaches to plurichiral oxacyclic systems, International Conference on Organic Synthesis (ICOS-11), 30 / 06-04 / 07 / 1996, Amsterdam (NL).
    • LORIN, P. ROLLIN, X. POISSON, S. MEUDAL, S. PILARD & W. LUIJTEN, Analyse structurale par spectrométrie de masse de sulfones osidiques, XVI èmes Journées de Spectrométrie de Masse, 17-19 / 09 /1996, Orléans.
    • LORIN & P. ROLLIN, Synthesis of chiral pyrrolidines. New approaches based on sugar-derived vinyl sulfides and vinyl sulfones, ESOC-10, 22-27 / 06 / 1997, Basel (Switzerland).
    • LORIN, Heterocyclic thioglyco-hybrids : versatile precursors for the synthesis of chiral oxa- and azacycles, conference for the firm Hoffmann-La Roche, 27 / 06 / 1997, Basel (Switzerland)*.
    • LORIN & P. ROLLIN, Synthesis from thiosugars of chiral THF-THF or THF-THP bicyclic building blocks, 8th Bratislava Symposium on Saccharides, 1-5 / 09 / 1997, Smolenice, (Slovaquie)*.
    • GUEYRARD, C. LORIN, J. MORAVCOVA & P. ROLLIN, A novel intramolecular migration in saccharidic sulfones : benzothiazol-2-yl group transfer through an ipso-substitution, ibid.
    • MORAVCOVA, R. BLAHOVA, P. STOIOVA, C. LORIN & P. ROLLIN, Synthetic studies of a pentofuranose with a fused pyrazolidine ring, ibid.
    • CASSEL, C. LORIN, M. RENARD, P. ROLLIN & H. VESCHAMBRE, Compared stereoselectivities in the chemical and biological oxidation of sugar-derived sulfides, Biotrans’ 97, 22-26 / 09 / 1997, La Grande Motte, France.
    • LORIN, Aza-heterocycles / thiosugar hybrids: prospects in stereocontrolled synthesis, conference for the firm Hoffmann-La Roche, 05 / 12 / 1997, Basel (Switzerland)*.
    • GUEYRARD, C. LORIN, J. MORAVCOVA, P. ROLLIN : Une nouvelle migration intramoléculaire chez les hétéroaryl sulfones osidiques, 5ème Journée Jeunes Chercheurs, 16 / 01 / 1998, Paris.
    • MORAVCOVA, R. BLAHOVA, P. STOIOVA, C. LORIN, P. ROLLIN, E. VANGREVELINGHE, L. MORIN-ALLORY : Stereostructural investigation of sugar-derived pyrazolidines by NMR and molecular modelling calculations, 8th Meeting on Stereochemistry, 19-22 / 04 / 1998 , Teplà (République Tchèque).
    • LORIN, O. INTES, P. ROLLIN : Chiral vinyl « thiocarbonates» as unexpected Michael acceptors in a ring closure process, 18th International Symposium on the Organic Chemistry of Sulfur (ISOCS-18), 13-18 / 07 / 1998.
    • AUCAGNE, C. LORIN, A. TATIBOUET, P. ROLLIN : Thiochimie des sucres – cyclisations de vinylsulfures osidiques, XIIIe journées de la Chimie et de la Biochimie des Glucides, 28-05 / 01-06-2000, Ambleteuse, France.
    • LORIN, R. GULLER, C. MUNSCH, J. SCHROER, Parallel three step solution synthesis of pharmaceutical active compounds, Combinatorial Chemistry 2000, 11-14/07/2000, London.
    • LORIN, Parallel synthesis and traditional chemistry in lead optimization, Combinatorial Chemistry 2000, 11-14/07/2000, Imperial College of London, UK*.
    • LORIN, Validity of experiments on down-scaled equipment combining high throughput experiments (HTE) and design of experiment (DoE) to accelerate process development, Optimising organic reactions and processes, 17-19/06/02, Hotel Royal Christiana, Oslo, Norway*.
    • JABLONSKI-LORIN, Validity of Experimental Results from Catalyst Screening and Yeast-Catalysed Biotransformation on Down-Scaled Equipment for Parallel Synthesis, The 3rd conference for Parallel Solution and Solid Phase Chemistry, 16-17/01/03, Hilton Basel, Basel, Switzerland*.
    • JABLONSKI-LORIN, A Few Examples of Applications in Bioorganic and Organic Chemistry Performed on the Syncore Workstation, Büchi’s Synthese- und Chromatographie-Seminar, 08/06/04, Kongresszentrum Basel, Switzerland*.
    • JABLONSKI-LORIN, Biosynthesis and Characterisation of N-hydroxy compounds phase II metabolites using UDP-glucuronyltransferases, Olten Meeting organised by Swiss Biotechnet, 15/11/06, Hotel Arte Olten*.
    • JABLONSKI, C. SIEBENHAAR,M. WASER, M. LIEBETANZ, S. GRABER, E. CONSTABLE, U. PIELES, G. GRUNDLER, M. HEIGHT, Flame Spray Pyrolysis for the Preparation of Manganese Oxide Nanocomposites, SCG, PolyColl 2011, 29.04.11, Geneva.
    • JABLONSKI, C. SIEBENHAAR,M. WASER, M. LIEBETANZ, S. GRABER, E. CONSTABLE, U. PIELES, G. GRUNDLER, M. HEIGHT, Manganese Oxide Hybrid Nanocomposites Used as Mild Oxidant and Recyclable Catalyst, SCG Fall Meeting, 13.09.12, ETH-Zürich.
    • JABLONSKI, S. STEBLER, G. GRUNDLER, U. PIELES,  R. OEHRLEIN AND Z. SZAMEL, Synthesis and mobility properties of new nanoparticles for colored e-readers, SNI Annual Meeting,  11-12/09/14, Lenzerheide, Switzerland.
    • JABLONSKI, S. STEBLER, G. GRUNDLER, U. PIELES, R. OEHRLEIN AND Z. SZAMEL, Synthesis and electrophoretic properties of nanoparticles linked to dendrimer-dyes branched structures, SCG, Polycoll 2015,  03/07/15, Uni Fribourg, Adolphe Merkle Institute.
    • JABLONSKI, S. STEBLER, G. GRUNDLER, U. PIELES, R. OEHRLEIN AND Z. SZAMEL, Synthesis and electrophoretic properties of nanoparticles linked to dendrimer-dyes branched structures, SCG Fall Meeting 2015,  04/09/15, EPFL Lausanne.
    • JABLONSKI, R. OEHRLEIN, Z. SZAMEL, Core Shell Nano-Particles for Colored e-Paper Applications, Innovation Landscape Nano, 09.09.15, FHNW Muttenz.

    Institut für Chemie und Bioanalytik

    Fachhochschule Nordwestschweiz FHNW
    Hochschule für Life Sciences
    Institut für Chemie und Bioanalytik

    Hofackerstrasse 30

    4132 Muttenz