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Projects, BioInterfaces

Multi-compartment nanofactories for on-site and on demand drug synthesis and delivery

We develop compartmentalized vesicles with internal compartments that can be triggered independently and selectively to release their cargo. Libraries of novel stimuli-responsive block co-polymers are prepared for vesicle formation, and release is actuated by external stimulus such as light, magnetic field, etc.

Projects, BioInterfaces

Nanocarriers for mRNA therapeutics

Combining the stability of polymers with transfection efficiency of lipids, we developed polymer-lipid hybrid nanoparticles, which can be stored as lyophilized powder and display long-term storage stability also in suspension. Lyophilization does not impair transfection efficiency.

Projects, BioInterfaces

Nanomedicine and theranostics

Diverse nanoparticle formulations based on polymers, lipids, and combinations thereof, loaded with (bio)therapeutics such as antimicrobial peptides, small molecule drugs, and nucleic acids are developed to combat infectious diseases and cancer. We further develop inorganic nanoparticles (metal and semiconductor) and drug-conjugated luminescent probes with cleavable linkers for simultaneous therapy and…

Projects, BioInterfaces

Tailor-made nanoparticles

Using top-down and bottom-up synthesis, encapsulation, surface engineering, and bioconjugation approaches, we develop nanoparticles with precisely defined and controlled size, morphology, composition, and surface functionality, and tailor them for the desired biological targets and functions.

Projects, Molecular Nanotechnology

ORACLE

The groundbreaking work that led to the emergence of metal-organic frameworks (MOFs) represents a major milestone in the design of materials with controlled atomic or molecular architectures. MOFs are organic-inorganic crystalline materials; they have attracted particular attention owing to their tremendously high surface area and tunable pore size, properties that…

Projects, Molecular Nanotechnology

Nymphe

Nymphe is a four-year European project dedicated to tackling environmental pollution by developing innovative bioremediation solutions.The ambition is to remove multiple pollutants (such as microplastics and pesticides in agricultural soil, and chlorinated solvents and petroleum hydrocarbons in groundwater and sediments in the industrial area) from different contaminated sites in Europe.In…

Projects, Molecular Nanotechnology

NANOdePET

Scanning electron micrograph of a polymer layer degraded by a nanobiocatalyst Despite widespread public awareness and increasingly stringent public policies, plastic use is increasing exponentially. Aside from massive fossil fuel consumption and greenhouse gas emissions, plastics pose a major environmental threat.In NANOdePET, the project partners…

Projects, Molecular Nanotechnology

Agriloop

The AgriLoop consortium aims to extend the agricultural production value of two major players of the global bioeconomy: the European Union and China, by eco-efficiently upgrading under-exploited residues into a portfolio of high added-value bio-products able to generate new bio-based markets or to compete with, and gain market share of, oil- and…

ICB news, Instrumental Analytics

Welcome to Dr. med. vet. Julia Lechmann

Dr. med. vet. Julia Lechmann Together with Prof. Stefan Gaugler, Dr. med. vet. Julia Lechmann will be working on dried blood spot (DBS) analysis in veterinary medicine at the FHNW. The aim of their project is to transfer the detection of various animal pathogens from liquid blood to DBS…

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