NanoCoat

Titanium and its alloys are the most frequently used biocompatible materials in medical engineering.

Accelerated osseointegration can be achieved by modifying the Ti surface with a layer of calcium phosphate (CaP). Current processes typically generate a relatively thick CaP (e.g., by plasma spray) and only a few thin coatings are available. We developed a cost-effective protocol for Ti surface modification with a thin CaP layer using a wet biomimetic route. The interface between implant and bone is one of the critical factors to achieve short healing time and long term stability. A ceramic micro- and nanostructured surface, strongly joined to the metal, is obtained.

Micrograph of the nanostructured Ti surface after modification with CaP. From A. Carino, et al, European Cells and Materials, Online Periodical, Collection 1; Meet the Expert Conference Abstracts, p2, (2019).

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Modified surface. From A. Carino, et al, European Cells and Materials, Online Periodical, Collection 1; Meet the Expert Conference Abstracts, p2, (2019).

Referenzen

A. Testino, M. de Wild, E. Müller, A. Carino, F. Dalcanale, P. Gruner, W. Moser, Biomimetic growth of calcium phosphate ceramics on Ti implants, Annual Report 2018, Supplement, Swiss NanoScience Institute, University of Basel, Nano Argovia Project A13.09 NanoCoat, 90-91 (2018).
A. Carino, A. Testino, E. Mueller, M. de Wild, F. Dalcanale, P. Gruner, W. Moser, B. Hoechst, Novel biomimetic approach for titanium surface treatment by calcium phosphate: Towards the production of implants with improved bioactivity, European Cells and Materials, Collection 4; SSB+RM Conference Abstracts (page 8) (2019).
A. Carino, A. Testino, E. Mueller, M. de Wild, F. Dalcanale, P. Gruner, W. Moser, B. Hoechst, Implant surface modification by a controlled biomimetic approach, European Cells and Materials, Online Periodical, Collection 1; Meet the Expert Conference Abstracts, p2, (2019).