Further articles
Colonic Vitamin Delivery
In recent years, growing evidence shows that the microbes in our body are highly involved in our overall health. Specially, gut microbiota is key to human diseases and health, and nutrition may influ-ence its composition and balance. Recent studies have shown that vitamins delivered to the colonic microbiota may prevent…
Cancer-specific Alternative Splicing Events
Novel diagnostic and prognostic biomarkers for different cancer types CanIso.netA new database to assess the impact of cancer-specific Most Dominant Transcripts (cMDT) using an isoform-specific interaction network. Alternative RNA splicing is a regulatory cellular mechanism to create multiple mRNA molecules from the same gene…
Biosynthesis Rescue
Synthetic glycolipids for the treatment of rare diseases GPI-Anchored Proteins Biosynthesis Rescue We established a synthetic strategy for the chemical synthesis of glycosylphosphatidylinositols having unsaturated lipids. This strategy was used in a project with the group of Prof. Taroh Kinoshita from Osaka University and the Max Planck…
Welcome to This Zahnd
This Zahnd After successfully defending his Bachelor-Thesis “Modeling-Based Approach Towards Quality by Design for a Telescoped Process” at the university of applied sciences FHNW-HLS (Project partner Siegfried AG), This joined us on September 19th 2022, strengthening the teams expertise in process…
Congratulations Ajmal Roshan for securing the Best Poster Award at the SNI Annual Meeting
Best Poster Award Ajmal Roshan attended the Swiss Nanoscience Institute annual meeting held in Lenzerheide and presented his work on self-assembled metal-organic networks as a poster securing the Best Poster Award. Congratulations Ajmal!…
Congratulations Fabrice Müller & Saskia Schmidt for performance a the Swiss Society of Toxicology
During the annual meeting of the Swiss Society of Toxicology in Basel, November 2021, the poster entitled “Investigation of the interplay between oxidative stress and antioxidant defense in 3-dimensional primary human liver microtissues” prepared by Joelle Hofer and presented by Fabrice Müller was awarded a poster prize. At the same…
Welcome to Dr. Abhijna Das
Dr. Abhijna Das After successfully defending her PhD-Thesis ““Controlling Phase Transitions in Langmuir Polymer Films” at the University of Freiburg (Germany) , Abhijna joined us on April 1st 2021, strengthening the teams expertise in material sciences.
Novel in vitro biomarkers for hepatotoxicity: exosomal miR-122
In vitro models for liver disease suffer from the lack of well-established and sensitive biomarkers of cellular damage. MicroRNAs (miRNAs; small noncoding RNAs) represent potential biomarkers for the detection of drug-induced liver injury in vivo and in vitro. Altered physiological state caused by disease or tissue damage results in altered release of exosomal- or protein-bound miRNAs, detectable in body fluids and cell culture media...