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Functionalization of artificial skin using femtosecond laser and optical coher-ence tomography, FHNW School of Engineering and Environment

School of Engineering and Environment


Artificial skin can be life-saving for people with severe burns, extensive wounds, or congenital skin disorders – especially when insufficient healthy skin is available for autografting. In this research project, the team is advancing large-scale functionalized artificial skin using highly precise technologies such as femtosecond lasers and optical coherence tomography. The goal is to improve the production, characterization, and biocompatibility of biomedical tissue while scaling the developed technologies towards future commercial applications.

skinholes

Background

Addressing skin defects remains a significant therapeutic challenge, particularly for patients with extensive wounds where autografting is limited. Laboratory-grown artificial skin has emerged as an effective solution for treating various skin conditions, including congenital diseases, trauma, and burns, and can be life-saving when the patient’s own skin is insufficient.

Goals

In this project, our objective is to develop large-scale functionalized artificial skin. To achieve this, we will focus on advancing processes for the production, micrometer-level precision characterization, and optimization of biomedical tissue.

Results

Functionalization of artificial skin using femtosecond laser is demonstrated, as well as improved biocompatibility.

Outlook: Scaling up of the developed processes and evaluation of avenues for commercialization of the developed technologies.

Project details

Type
Research project
University
Hochschule für Technik und Umwelt FHNW / Institute of Product and Production Engineering
Partner
University of Zurich
Funding
Innosuisse
Volume
CHF 845’980.25
Running time
18 months, started August 1st, 2025
Management
Prof. Dr. Bojan Resan
Collaboration
Prof. Dr. Bojan Resan, FHNW,
Dr. Manuel Zeyen, FHNW,
Armin Stumpp, FHNW,
Dr. Thomas Biedermann, Universität Zürich,
Amina Ben Nejma,
Dr. Luca Pontiggia

Kontakt

Bojan Resan

Prof. Dr. Bojan Resan

Dozent für Laser-Technologie
Phone
+41 56 202 85 92 (Direct)
E-Mail
bojan.resan@fhnw.ch

School of
Engineering and Environment FHNW University of Applied Sciences and Arts Northwestern Switzerland

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