EDUCATION

• 2005 – 2009 Ph.D. in Computational Biology, European Bioinformatics Institute, University of Cambridge, UK
• 2000 – 2005 Diploma in Bioinformatics, Depart. for Hospital & Clinical Eng., Environmental Technology & Biotech, University of Applied Science Giessen-Friedberg, Germany

CURRENT POSITION(S)

• since 08/2022: Lecturer and Group Leader, Institute for Chemistry and Bioanalytics, School for Life Sciences, University of Applied Sciences and Arts Northwestern Switzerland, Muttenz, Switzerland.
• since 04/2021: Group Leader, Swiss Institute of Bioinformatics, Lausanne, Switzerland.

PREVIOUS POSITIONS

• 2017 – 2022 Head of Clinical Bioinformatics, Department of Pathology and Molecular Pathology, University Hospital Zurich, Switzerland
• 2013 – 2017 Senior Postdoc, Institute of Molecular Life Science, University of Zurich, Switzerland
• 2012 – 2013 Research Scientist, Institute of Biochemistry, ETH Zurich, Switzerland
• 2009 – 2012 Postdoc, Institute of Molecular Systems Biology, ETH Zurich, Switzerland

• 2022 EMDO Stiftung Zürich, Switzerland, Research Grant
• 2019 Zürcher Krebskommission, Switzerland, Research Grant
• 2017 EMBO Installation Grant, Heidelberg, Germany
• 2017 Best presentation award at ISMB 2017, Prague, Czech Republic
• 2005 EMBL Pre-doctoral Fellowship
• 2005 FTG e.V. Certificate for 2nd best diploma degree

• 2022 Founder and Organizer, "Clinics meets Data Science Symposium 2022", Zurich
• 2021 Founder and Organizer, "Clinics meets Bioinformatics Symposium 2021”, Zurich
• 2015 Organizer, Scientific symposium, "First Symposium of the Swiss EMBL Alumni Chapter”, Zurich
• 2013-2017 Founder and Organizer of NanoTalks, Scientific talks for the lay public, Zurich

Google Scholar

• ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium. (2020). Pan-cancer analysis of whole genomes. Nature, 578(7793), 82–93.
• Kahraman, A., Karakulak, T., Szklarczyk, D., von Mering, C. (2020), Pathogenic impact of transcript isoform switching in 1,209 cancer samples covering 27 cancer types using an isoform-specific interaction network, Sci Rep 10, 14453.
• Leuenberger, P., Ganscha, S., Kahraman, A., Cappelletti, V., Boersema, P. J., Mering, von, C., et al. (2017). Cell-wide analysis of protein thermal unfolding reveals determinants of thermostability. Science, 355 (6327).
• Feng, Y.*, De Franceschi, G.*, Kahraman, A.*, Soste, M., Melnik, A., Boersema, P., Polv`erino de Laureto, P., Nikoaev, Y., Oliveira, A.P., Picotti, P. (2014). Global analysis of protein structural changes in complex proteomes. Nature Biotech 32, 1036-1044.
• Herzog, F.*, Kahraman, A.*, Bohringer, D.*, Mak, R., Bracher, A., Walzthoeni, T., Leitner, A., Beck, M., Hartl, F. U., Ban, N, Malmstroem, L., Aebersold, R. (2012). Structural probing of a protein phosphatase 2A network by chemical cross-linking and mass spectrometry. Science 337, 1348–1352.
• Leitner, A., Kahraman, A.*, Walzthoeni, T.*, Herzog, F., Rinner, O., Beck, M., Aebersold, R. (2010). Probing native protein structures by chemical cross-linking, mass spectrometry and bioinformatics. Mol Cell Proteomics 9, 1634-1649
• Kahraman, A., Morris, R. J., Laskowski, R. A. & Thornton, J. M. (2007). Shape variation in protein binding pockets and their ligands. J Mol Biol, 368, 283-301.
• Morris, R. J., Najmanovich, R. J., Kahraman, A., Thornton, J. M. (2005). Real spherical harmonic expansion coefficients as 3D shape descriptors for protein binding pocket and ligand comparisons. Bioinformatics 21, 2347-2355

• since 2022: Associate Editor in Frontiers Biological Modeling and Simulation, Lausanne, Switzerland
• 2020-2021: Editor of Frontiers Molecular Biosciences Research Topic: Alternative Splicing in Health and Disease, Lausanne, Switzerland
• since 2020: Editorial Board Member of Journal BioMedInformatics, Basel, Switzerland

• Platform Co-Leader, Data Science: Biotechnet Switzerland
• Group Leader: Swiss Institute of Bioinformatics
• Member: Deutsche Gesellschaft für Pathologie

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