Boost your skills in continuous chromatography. Train hands-on with leading experts and gain a profound understanding of continuous chromatography for mAbs, Oligonucleotides, Peptides and Viral Vectors.
Factsheet
- Degree
- Confirmation of participation
- Learning environment
- Onsite
- Next start
- 8.9.2026
- Duration
- 3 days (8.-10.9.2026)
- Teaching languages
- English
- Venues
- FHNW Campus Muttenz
- Fee
- CHF 3 000
At a glance
- Train hands-on with twin column equipment for capture and polishing processes for biomolecules.
- Learn cutting-edge techniques in continuous chromatography.
- Benefit from leading experts with academic and industrial backgrounds.
- Expand your network and enjoy an inspiring evening programme.
Aims and benefits
You will deepen your knowledge of continuous chromatography for biomolecules with hands-on lab experience using industry-grade equipment.
By the end of the seminar you will be able to:
- explain the fundamentals of large-molecule chromatography
- design, run and optimise multi-column chromatography processes
- evaluate process performance and scale up
- apply your knowledge directly through practical lab training
Target audience
This seminar is designed for separation scientists and process development engineers from industry and academia. You already have some experience with single-column chromatography, you want to broaden your understanding of chromatographic processes and learn new and more efficient ways to separate and polish biomolecules. If you’re looking to enhance your expertise and implement continuous chromatography in real-world settings, this seminar is for you.
Structure and programme contents
This three-day seminar combines theory, hands-on laboratory work and expert-guided analysis. You will work directly with Contichrom CUBE twin-column separation and purification systems. Each day blends lectures with practical lab sessions, ensuring a rich and immersive learning experience.
This workshop does not cover 4-zone SMB, chiral and small molecule separations.
Day 1: Production of Biotherapeutics
- Fundamentals of Large-Molecule Chromatography
- Intro to Continuous Chromatography (CaptureSMB)
- Lab workshop: CaptureSMB
- Modelling and Simulation
- Digitalisation
- Evening programme/Dinner
Programme
Time | Content |
|---|---|
09.00-09.10: | Welcome and Housekeeping |
09:10-09:45 | Lecture 1: Production of Bio-Therapeutics |
09.45-10.45 | Lecture 2: Fundamentals of Large-Molecule Chromatography |
10.45-11.00 | Coffee break |
11.00-12.30 | Lab Workshop 1 Contichrom CUBE and Batch Capture |
12.30-13.30 | Lunch |
13.30-14.15 | Lecture 3: Continuous Countercurrent Chromatography |
14.15-15.00 | Lecture 4: Affinity (Capture) Chromatography |
15.00-15.15 | Coffee Break |
15.15-17.00 | Lab Workshop 2: CaptureSMB |
17.00-18.00 | Lecture 5: Performance Evaluation of Continuous Chromatography |
18.00 | Reception |
Day 2: Hands-on Chromatography
- Flowthrough and Frontal Chromatography
- Integrated Chromatography
- Continuous Chromatography: MCSGP
- Lab workshop: MCSGP
- Performance Evaluation
- Lab workshop: CaptureSMB Evaluation
- N-Rich
- Evening programme/Dinner
Programme
Time | Content |
|---|---|
09.00-10.30 | Lecture 6: Bind and Elute (Polishing) Chromatography |
10.30-10.54 | Coffee break |
10.45-12.00 | Lab Workshop 3 Linear Gradient Chromatography |
12.00-13.00 | Lunch |
13.00-13.30 | Lab Workshop 4 Evaluation Center |
13.30-14.30 | Lab Workshop 5 Evaluation of Batch and CaptureSMB |
14.30-15.00 | Presentation of Capture Results by Groups |
15.00-15.15 | Coffee break |
15.15-17.30 | Lab Workshop 6 MCSGP |
17.30 | Social programme + Dinner |
Day 3: Workshop and Wrap-up
- Modelling Workshop
- Lab workshop: MCSGP Evaluation
- Scale-up (MCSGP)
- Wrap-up
Programme
Time | Content |
|---|---|
09.00-10.30 | Lecture 7: Integrated Continuous Manufacturing & Process Digitalization |
10.30-10.45 | Coffee break |
10.45-12.00 | Lecture 8: Modelling and Simulations |
12.00-13.00 | Lunch |
13.00-14.00 | Lab Workshop 7 Evaluation of MCSGP |
14.00-14.30 | Presentation of Polishing Results by Groups |
14.30-15.15 | Lecture 9-I: Scale-up of continuous chromatography (part I) |
15.15-15.30 | Coffee break |
15.30-16.15 | Lecture 9-II: Scale-up of continuous chromatography (part II), Guest Speaker: Ralf Eisenhuth, Bachem, Switzerland |
16.15-16.45 | Lecture 10: N-Rich Process for Isolation of Impurities |
16.45-17.00 | Course Wrap-up |
17.00-17.30 | Guided lab tour (optional) |
Lecturers
Massimo Morbidelli, Ph.D.
Professor of Chemical Reaction and Separation Technologies at the Department of Chemistry, Politecnico di Milano. A pioneer in preparative continuous chromatography, in particular in the application of multicolumn technologies for protein purification in the pharma industry, Prof. Morbidelli has co-authored over 500 research articles and four books. He serves as associate editor for the Industrial & Engineering Chemical Research journal of the ACS and is the recipient of the 2005 RH Wilhelm award from the AIChE and of the 2014 Gerhard Damkoehler medal of DECHEMA. He is a co-founder of ChromaCon AG in Zurich.
Thomas Müller-Späth, Ph.D.
Director of R&D at ChromaCon AG in Zurich. After an assignment at Bayer Healthcare, Thomas completed his doctoral work on continuous chromatography of biomolecules in the group of Prof. Morbidelli, and co-founded ChromaCon AG to bring the technology to the market. He has been working on research projects with industrial partners, development of chromatography processes and equipment, and IP management. He has presented on continuous chromatography at numerous workshops and conferences and has co-authored over 20 publications and patents.
Supervisors and Tutors
Supervision and support throughout the seminar is provided by Sebastian Vogg, Richard Weldon and Lars Aumann.
Organisational matters
Format
The seminar comprises presentations and interactive workshops using laboratory-scale Contichrom CUBE twin column separation & purification systems. Subject matter experts and graduate assistants will support the participants during the interactive workshops and data analysis sessions.
The seminar fee includes lecture summaries in paper and electronic formats, materials used during the workshop, lunch and coffee breaks, as well as participation in the evening programme/dinner. It does not include accommodation, travel costs or catering other than indicated above.
If you need to book accommodation we recommend, among others, the following hotels near FHNW Campus Muttenz:
Hotel Baslertor Muttenz
Hotel b_smart_motel Basel
Moevenpick Basel
Programme partner
Downloads
General Documents
All general documents can be found here.
Advising and information events
Contact
Prof. Dr. Thomas Villiger
- Phone
- +41 61 228 52 46
- thomas.villiger@fhnw.ch
Registration
Seminar Continuous Chromatography for Biotherapeutics8 September 2026
- Date
- 8.9.2026–10.9.2026
- Duration
- 3 Days
- Place
- FHNW Campus Muttenz
- Final application date
- 31.7.2026